The club was established in 1993 under the name Academie Amis du Monde.
In 2021, AS OTR Lomé represented Togo in the inaugural edition of the CAF Women's Champions League.
The club was convincingly defeated (5-1) in the semifinals of the qualifying tournament for the UFOA-B zone by the Rivers Angels, failing to qualify for the continental final phase.
However, Amis du Monde secured third place by winning the third-place playoff (2-0) against the USFA.
[1] In the 2021-2022 championship, Amis du Monde emerged victorious in all their matches, including the final against Athlèta (1-0), clinching yet another title.