51767942ENSG00000135390ENSMUSG00000062683Q06055P56383NM_001002031NM_005176NM_001330269NM_026468NP_001356684NP_001356685NP_001356686NP_001356687NP_080744The ATP5MC2 gene is one of three human paralogs that encode membrane subunit c of the mitochondrial ATP synthase.

[5][6] This gene encodes a subunit of mitochondrial ATP synthase.

ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel.

The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits.

There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins.