518228033ENSG00000154518ENSMUSG00000018770P48201P56384NM_001689NM_001002258NM_001190329NM_001002256NM_001301721NM_001301722NM_175015NP_001002258NP_001177258NP_001680NP_001288650NP_001288651NP_778180The ATP5MC3 gene is one of three human paralogs that encode membrane subunit c of the mitochondrial ATP synthase.

ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel.

The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3.

Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein.

Alternatively spliced transcript variants encoding the same protein have been identified.