A Long Return, also known by the title Largo Retorno in Spain, is a 1975 Spanish romantic film, directed by Pedro Lazaga.

A vibrant young college student, Anna (Lynne Frederick), catches eye of architect, David Ortega (Mark Burns), at an orchestra show.

Soon after their Venice honeymoon, Anna begins acting strange; experiencing sudden fatigue, grogginess, and memory loss (even forgetting her best friend).

Eventually Anna is hospitalized and doctors diagnose her condition as lipomatosis of the nervous system, a rare and deadly disease that is quickly killing her.

For forty agonizing and heart aching years, David remains faithful to Anna and waits for a cure to be found.

The ice is broken when her best friend, Irene (now well past her 60s), visits her and informs her of what has happened in the last forty years (such events like Anna's parents dying and the inevitable changes David has succumb to with age).

When she is released from the hospital, Irene takes her to David, and much to his delight, Anna greets him with overflowing love and affection.

Upon release the film received mixed to favorable reviews from critics, who praised Burns's and Frederick's performances but jeered some of the science and medical fiction elements.