A Virgin with a Unicorn (Fanciulla e l'unicorno) is a fresco painting by the Italian Baroque artist Domenichino, completed between c. 1604 and 1605.

[2] A Virgin with a Unicorn was created for the decoration for Galleria Farnese under the direction of Annibale Carracci, who died a few years later after the piece was finished.

It is the undisputed work of his student Domenichino,[2] but it may be doubtful whether it was his sole effort.

The artist highlights the shyness of both subjects, as the scene is set at the edge of the woods instead of the center of the landscape.

The gentle atmopshere of the piece is in contrast to Carracci's bloody scenery of his Galleria Farnese.