Mohamed Abdel Ghani el-Gamasy (Arabic: محمد عبد الغني الجمسي, 9 September 1921 – 7 June 2003) was an Egyptian Field Marshal and the former minister of defense of Egypt.

During the War of Attrition, in March 1969, then-President Gamal Abdel Nasser appointed el-Gamasy as commander of the Second Field Army.

El-Gamasy later wrote that Nasser should have deconstructed Amer's autonomous web of control in the armed forces following the Egyptian military failure during the Suez Crisis in 1956.

He was also appointed by Anwar Sadat as the head of the group that participated in the disengagement talks on 28 October, at "Kilometer 101".

Reportedly, he was sad for the lost souls at the war when the American secretary of state Henry Kissinger announced that the president Sadat agreed to pull the main part of the Egyptian forces from the east side of the Suez Canal in exchange of the withdrawal of Israeli forces from the west side of the Suez Canal and retreat back into the depth of Sinai.