Born in Alexandria, Egypt, Nader started his career at Maine East High School, before transferring to Niles North.

[1] He averaged 23.8 points, 8.6 rebounds and 2.8 assists per game as a senior at Niles North and led the Vikings to a 24–6 record and their first sectional championship and Central Suburban League titles in the school's 47-year history.

He started 18 of the 19 games he played in, leading the team in scoring at 13.1 points while averaging 5.6 rebounds, 1.3 assists and shooting 77.2 percent from the free-throw line (44-57 FT).

[5] In spite of Nader's contributions, the Huskies finished last in the MAC West division and had a 5–15 team record overall, and it was reported that he would be transferring to another school.

Nader averaged 21.3 points, 6.2 rebounds and 3.9 assists in 40 games, propelling the Red Claws to a 29–21 record and the Eastern Conference's second seed in the 2017 NBA D-League Playoffs.

[18] On November 16, 2020, the Thunder traded Nader and Chris Paul to the Phoenix Suns for Kelly Oubre Jr., Ricky Rubio, Ty Jerome, Jalen Lecque, and a protected 2022 first-round pick.

[19] After getting a concussion in a December 2020 preseason against the Utah Jazz,[20] he made his season debut on January 11, 2021, against the Washington Wizards.

[22] On March 4, he had a near-double-double performance with 14 points and a career-high 9 rebounds off the bench in another blowout victory over Golden State, this time ending with a 120–98 win.

[25] On December 12, 2023, Nader signed with the South East Melbourne Phoenix of the Australian National Basketball League (NBL) for the rest of the 2023–24 season.

[26] Nader is eligible for the Egypt national team and has confirmed that he would be making his debut at the 2023 FIBA Basketball World Cup.

[28] Nader moved with his family to the United States at the age of 3 and considers Skokie, Illinois his hometown.