[3] Ephraim Abel Kayembe was born in 1973 in Dzoole Village, Dowa, Malawi where he grew up and had his early education.
[9][10] During that period, he participated in bilateral meetings over the issue of Lake Malawi boundary dispute with Tanzania.
He also chaired inter- ministerial committee that reviewed and developed new governance framework for Malawi.
[11] Abel Kayembe in 2019 contested the Dowa West Constituency in the 2019 Malawian general election for the parliamentary seat under Malawi Congress Party.
[13][14] Before winning the 2019 Parliamentary election, Ephraim worked as an adjunct Lecturer of Public Policy Development, Organizational Change Management and Political Economy at Malawi Institute of Management and DMI St. Eugene University of Zambia.