Amongst the roles she created were Amelia di Egmont in the 1882 posthumous premiere of Donizetti's Il duca d'Alba and Élisabeth de Valois in the 1884 revised version of Verdi's Don Carlos.

[5] Later in 1879 she sang in Buenos Aires at the Teatro Colón and in Rio de Janeiro at the Theatro Dom Pedro II with Angelo Ferrari's Italian opera company whose singers included Francesco Tamagno.

In his review of the premiere, the critic for La Gazzetta Musicale di Milano wrote: "Signora Bruschi-Chiatti with her beauty and a voice that was brilliant, fresh, robust and a true soprano ... sang with warmth and passion.

"[2] On 10 January 1884, Bruschi-Chiatti appeared at La Scala as Élisabeth de Valois in the premiere of Verdi's revised version of Don Carlos with Francesco Tamagno in the title role.

Contemporary accounts noted that she had very evident stage fright on the opening night (a problem she also had at the premiere of Il duca d'Alba) which negatively impacted her performance in the first three acts.