Constructed in the 1970s, the mosque was established to cater to the Muslim community in Abossey Okai and neighboring areas such as Sabon Zango.

[1][2] The construction of the Central Mosque in Accra aimed to provide a place of worship for the growing Muslim population in the Abossey Okai locality.

[4][5] For a significant period, the Abossey Okai Mosque served as the venue for Friday prayers led by the Chief Imam of Ghana, Sheikh Osman Nuhu Sharubutu.

[6][7] In 2020, the Vice President of Ghana, Mahamudu Bawumia promised to carry out a renovation of the Abossey Okai Central Mosque.

[8] He made the pledge when he addressed a Muslim congregation at an Islamic Thanksgiving ceremony held on Friday at the mosque.