Dr. Abraham Cornelius, one of the senior scientists for Weapon X, is employed by the mysterious Professor Andre Thorton and partnered with a young Dr. Carol Hines.

Sometime after World War II, Wolverine is taken in by the project and Cornelius is assigned with the task of perfecting and using a technique that would bond the indestructible alloy adamantium to human bone cells.

[1] Years later, Japanese crime lord Matsu'o Tsurayaba and his allies, including former Weapon X scientist Doctor Cornelius, resurrect the Russian super-soldier Omega Red.

In order to stabilize his mutant power, Omega Red requires the Carbonadium Synthesizer, a device stolen from him by Team X decades earlier.

It is not confirmed if he has anything to do with the rogue Weapon X agents led by Tara who hunt Wolverine all over Manhattan and participate with the coup against the President of the United States.

[7] In Ultimate Origins, it is revealed that Cornelius' experiments on Wolverine created the mutant gene, which he claims is how humanity will survive.

[8][9] Apart from the scarring, the Ultimate Marvel version of Doctor Cornelius resembles Professor Thornton (the original Director of the Weapon X project in the mainstream universe).