Abram Creek is a 19.4-mile-long (31.2 km)[5] tributary stream of the North Branch Potomac River in Grant and Mineral counties in West Virginia's Eastern Panhandle.

Abram Creek enters the North Branch Potomac River at Harrison, West Virginia, across from Shallmar, Maryland.

Abram Creek drains 44.19 square miles (114.5 km2) of area, receives about 43.2 in/year of precipitation, has a topographic wetness index of 410.24 and is about 75.9% forested.

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