[2] Because the stream flows through several small farms, Buffalo Creek primarily serves agriculture purposes with segments used for livestock watering.
A historical highway marker along West Virginia Route 28 marks the approximate location of the stockade fort.
The stream's headwaters lie along the eastern flanks of South Branch Mountain southwest of Three Churches.
From its source, Buffalo Creek meanders in a southwest direction along the forested foot of South Branch Mountain.
The stream winds a northwesterly path through a gorge that leads it through the Buffalo Hollow in South Branch Mountain.