[1]: 597  Acquired progressive lymphangioma may develop following radiation therapy, surgery, trauma, inflammation, and tick bites.

Acquired progressive lymphangioma appears as a slowly growing erythaematous to brownish, bruise-like, macule, plaque, or nodule typically located on the legs, head or neck.

[3] Acquired progressive lymphangioma has been known to develop after radiation therapy,[4] surgery,[5] trauma,[6] femoral arteriography,[7] inflammation,[8] and tick bites.

[9] Because acquired progressive lymphangioma has been described following various traumas, it is thought to be a response to various inflammatory stimuli rather than a real neoplasm.

[10] Another possible pathogenic explanation is hormonal stimulation, as quickly growing lesions have been observed in numerous pubescent and prepubescent individuals.