It is published by Wiley-Blackwell on behalf of the Foundation Acta Paediatrica, based at the Karolinska Institute in Sweden.

The journal was established in 1921 and renamed Acta Paediatrica Scandinavica in 1964, returning to its original title in 1992.

[1] At the end of Zetterström's tenure as editor in the early 2000s, nearly two thirds of papers were authored by non-Nordic researchers.

[2] The journal is owned by the non-profit Foundation Acta Paediatrica, which is hosted by the Karolinska Institute, where all the editors-in-chief have been professors and the editorial office has always been based.

[2][1][3] In addition to its ordinary issues the journal has published nearly 500 supplements, primarily doctoral dissertations authored by paediatricians from the Nordic countries in the early to mid 20th century.