The apostolic decree from the Council of Jerusalem (Greek plural: δογματα (dogmata), commonly used for a "formal decision by a civic assembly") is mentioned for the last time.

[11] This section records the journey out of Paul's previous mission area ('region of Phrygia and Galatia' in verse 6) in the center and southern part of Anatolia, approaching the north-west corner of Asia Minor following ancient trade routes, one of which reached north of Antioch, leading "westwards down the Lycus Valley towards Ephesus".

[11] The absence of a preaching account along this part of the journey indicates that they were continually waiting for guidance, which finally came to Paul when they arrived in the port city of Troas, in a vision of a call for help from the man of Macedonia.

[14] The details of sea travel include the specific jargon of seafaring ('set sail', 'took a straight course', verse 11) and every port of call (Samothrace, Neapolis).

From Neapolis, the journey is by land along Via Egnatia, the Roman road connecting the northern Aegean cities (Philippi, as well as Amphipolis, Apollonia, and Thessalonica in Acts 17:1) to the ports at Adriatic Sea.

Nevertheless, the spirit of divination (Ancient Greek: πνεῦμα Πύθωνα, romanized: pneuma Pythōna[26]) affirmed for some days that Paul and Silas were servants of the Most High God.

Acts 22:22–29; 25:1–12), which higher standards of legal treatment than other people in the empire should prevent him and his companion to be publicly humiliated, and the violation of this could result in severe punishment for the magistrates (verse 37).