[3] The rapper MF DOOM gave Lough his first big break at age 19 when he let him direct two music videos from his debut solo studio album Operation: Doomsday[4] In 2002, Lough expanded his New York University thesis project to create Bomb the System, starring Mark Webber, Gano Grills, and Jaclyn DeSantis.
[6] In 2007, Lough wrote and directed Weapons starring Nick Cannon and Paul Dano and a host of upcoming young actors and actresses.
[7] Weapons was an experiment in non-linear storytelling tackling the problem of youth violence, and premiered in competition at the 2007 Sundance Film Festival, where it was nominated for the Grand Jury Prize.
The film is equally devoted to thirty years of Jamaican music and culture, and was narrated by Academy Award winner Benicio Del Toro.
[15] Lough followed up this film with Alt Right: Age of Rage a documentary about the Alt-Right movement that ended in tragedy at the Unite the Right Rally in Charlottesville, Virginia where his crew was caught in the melee.
[16] In 2019, Lough Executive Produced the first feature from his long-time editor Alex Lee Moyer, TFW NO GF, an exploration of Incel culture in America.