[2] He and brother Josh divided their childhood living between their father in Queens and their mother and stepfather in Manhattan upon their parents' divorce.

[2] He attended Columbia Grammar & Preparatory School[2] and graduated from the Boston University College of Communication in 2008.

[10] Uncut Gems, Josh and Benny's next film, starred Adam Sandler, Lakeith Stanfield and Julia Fox and was executive produced by Martin Scorsese.

[13] The show, in which they also starred, received critical acclaim,[14][15] and Safdie earned an Independent Spirit Award nomination for Best Supporting Performance in a New Scripted Series.

[17] In 2020, he appeared in Pieces of a Woman,[18] and in 2021 had a large supporting role in the Paul Thomas Anderson film Licorice Pizza.

[19] In 2022, Safdie appeared in Claire Denis' romantic thriller Stars at Noon,[20] and as Nari in the Disney+ miniseries Obi-Wan Kenobi.