The Mamluks responded by sending a force under Commander and Chief Uzbek, and besieged Adana.

The Ottoman Empire had launched a campaign in 1485 against the Mamluk holdings in Southern Turkey and in Cicilia Armenia, seizing areas such as Adana.

In order to respond, Sultan Qaitbey had Atabeg Uzbek launch a counter offensive.

Hersek-oglu was the son of Stjepan Vukčić, Duke of Herzegovina, who was sent as a hostage to the court of Mehmed II.

When Bayezid seized power, he allowed Kersek-oglu to marry one of his daughters, and also granted him a high position.