16011771ENSG00000196961ENSMUSG00000060279O95782P17426NM_014203NM_130787NM_001077264NM_007458NP_055018NP_570603NP_001070732NP_031484AP-2 complex subunit alpha-1 is a protein that in humans is encoded by the AP2A1 gene.

[5] This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP2 adaptors) complex found in clathrin coated vesicles.

Alternative splicing of this gene results in two transcript variants encoding two different isoforms.

A third transcript variant has been described, but its full length nature has not been determined.

[6] Adaptor-related protein complex 2, alpha 1 has been shown to interact with DPYSL2[7] and NUMB.