[1][2] Her parents were Rebecca and Henry Lewis, a wealthy farmer and rancher in Capinteria.
[5][6] While at Berkeley, she founded and was the first president of the Prytanean Women's Honor Society, with faculty advisor Mary Bennett Ritter, in the fall of 1900.
[8][10] She continued with her studies, enrolling in the Henry Shaw School of Botany at Washington University in St. Louis, earning an M.Sc.
[17][18] While at Standford, she was admitted to Sigma Xi science and engineering honor society, as a graduate student in botany.
[21][22][20] In July 1918, Grant taught at the summer session of the Fresno State Normal School.
[25][24] From February 1926 to 1930, she was head of the department of botany at Huguenot University College in Wellington, South Africa.
[29] On August 17, 1905, Lewis married George Francis Grant of Tuolumne County, California in Carpinteria.
[32] In March 1917, she made presentations and distributed petitions against the proposed California legislation that would allow hunters to kill beneficial birds that ate insects.