Adenosine reuptake inhibitor

An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs).

[1][2][3] This in turn leads to increased extracellular concentrations of adenosine and therefore an increase in adenosinergic neurotransmission.