[4] Pedernera was the natural conductor of both the famous River Plate team known as La Máquina ("The Machine"), with whom he won several Argentine and South American titles, and the Millonarios team called Ballet Azul ("Blue Ballet") that won the Small Club World Cup in 1953 among many others Colombian titles.

Pedernera's play with the Argentina national team, helped win the Copa América in 1941 and 1946, the latter tournament being named the Best Player.

[7] Pedernera usually played as an inside forward and was renowned for his technique and ability to create chances for other players, whilst also being a prominent goalscorer.

Still with the Club Atlético River Plate, he played with the likes of Ángel Labruna, José Manuel Moreno, Félix Loustau, and Juan Carlos Muñoz.

He also collaborated with Hugo Reyes, Antonio El Maestrico Báez, Néstor Rossi, and Alfredo Di Stéfano who he would later be teammates with them for CD Los Millonarios in Colombia, but first, in 1947, he was offered a million pesos to play for Atlanta of Buenos Aires.

The press of Bogotá received Pedernera well and commented the next day that "El Maestro" ("The Teacher") was "a phenomenon, an artist, a master of passing, and a show of intelligence.

After Carlos Aldabe retired as coach from Millonarios Pedernera took over as player-manager and was in this position instrumental in winning the three consecutive championships from 1951 to 1953 and the Copa Colombia of 1953.

[8] In 1993, he published his autobiography named "El fútbol que viví ... y que yo siento" (the football I lived ... and I feel), assisted by journalist Alejandro Yebra.

In 1994, Pedernera was reunited for the last time with his lifelong friends Alfredo Di Stéfano and Pipo Rossi at the Feria Internacional del Libro in Bogotá.