Adramyttium[nb 1] (Greek: Ἀδραμύττιον Adramyttion, Ἀδραμύττειον Adramytteion, or Ἀτραμύττιον Atramyttion) was an ancient city and bishopric in Aeolis, in modern-day Turkey.

The site of Adramyttium was originally settled by Leleges, the indigenous inhabitants of the Aegean littoral, and people from the neighbouring region of Mysia.

[3] In 422 BC, Pharnaces, the satrap of Hellespontine Phrygia, offered asylum to exiles from the island of Delos, who settled in the city.

[7] Mytilene retained control of Adramyttium until 386 BC, after which the city formed again part of the Persian Empire by the terms of the Peace of Antalcidas.

[10] After Alexander's death in 323 BC, his empire was divided among the Diadochi at the Partition of Babylon, and Leonnatus was appointed satrap of Hellespontine Phrygia.

[13] Adramyttium and Hellespontine Phrygia remained under the control of Antigonus until the Fourth War of the Diadochi; the city was taken by force by Prepelaus, a general of Lysimachus, Basileus of Thrace, in 302 BC.

[16] Adramyttium came under the control of the Attalid dynasty of Pergamon during the rule of Eumenes I, a nominal vassal of the Seleucid Empire, in the mid-third century BC.

[17] The alliance between Attalus I, Eumenes's successor, and Rhodes during the Cretan War led Philip V, King of Macedonia, to invade Attalid Pergamon and pillage the countryside surrounding Adramyttium in 201 BC.

In 190 BC, Antiochus III plundered the countryside surrounding Adramyttium, but the appearance of a Roman–Pergamene fleet prevented him from taking the city.

[29] According to the Acts of the Apostles, whilst en route to Rome, St. Paul departed Caesarea Maritima on a ship from the city of Adramyttium which took him to Myra in Lycia.

[32] In early 715, soldiers of the theme of Opsikion mutinied and travelled to Adramyttium where they proclaimed Theodosius, a praktor (tax-collector),[33] as emperor.

[36] Upon discovering that Malik Shah, Sultan of Rum, planned to invade in early 1112, Emperor Alexios I Komnenos sent an army to Adramyttium ahead of him as he travelled to the Chersonese peninsula.

[40] The megas doux Michael Stryphnos levied a fine on the Genoese merchant Cafforio,[41] who subsequently raided the cities of the Aegean Sea and sacked Adramyttium in 1197.

[42] The Byzantine magnate Theodore Mangaphas attempted to seize the city but was defeated by Henry of Flanders at the Battle of Adramyttium on 19 March 1205.

[44] Henry of Flanders regained Adramyttium in October 1211 after his victory over the Nicaean emperor Theodore I Laskaris at the Battle of the Rhyndacus.

[47] The Treaty of Nymphaeum of 1261 granted the Republic of Genoa trading privileges, such as marketplaces, at Adramyttium, among other Aegean cities.

[50] Following victory over the Byzantines at the Battle of Bapheus in July 1302, the founder of the Ottoman dynasty, Osman I, raided the countryside surrounding Adramyttium.

[56] Kiepert argued that this move took place in 1109, however, scholars note that it is not stated in contemporary sources that the city was rebuilt inland.