The α2C receptor has been reclassed from α1C, due to its greater homology with the α2 class, giving rise to the somewhat confusing nomenclature.
[2] In general, a primary or secondary aliphatic amine separated by 2 carbons from a substituted benzene ring is minimally required for high agonist activity.
Other drugs affect the uptake and storage mechanisms of adrenergic catecholamines, prolonging their action.
The following headings provide some useful examples to illustrate the various ways in which drugs can enhance the effects of adrenergic receptors.
According to receptor selectivity they are two types: These are agents that increase neurotransmission in endogenous chemicals, namely epinephrine and norepinephrine.
The most common mechanisms of action includes competitive and non-competitive reuptake inhibition and releasing agents.