Affinity capture is a technique in molecular biology used to isolate desired compounds based on their chemical properties and a solid substrate.
[1] Commonly, plates out of solid materials such as glass are coated with various reagents to allow for covalent bonding of a capturing molecule such as an antibody.
Washing the plate and removing the desired compound completes the purification process.
[2] Affinity capture has been used to isolate proteins by means of binding a peptide sequence to the solid substrate, thus allowing for protein capture.
[3] The process has also been examined for potential automation, but the unique circumstances for any given experiment may impede reproducibility.