The series depicts, in mockumentary style, the behind the scenes goings-on at the office of the late-night talk show Chelsea Lately.

Celebrity guest stars regularly appear, playing parody versions of themselves, interacting with Chelsea and the cast.

[1] After Lately is a faux reality show, purporting to expose the behind-the-scenes goings-on of Chelsea Handler's hit, late-night, E!

The camera shots are intentionally meant to mimic a documentary-style, fly-on-the-wall point-of-view (a la, The Office and Parks and Recreation).

The various cast members, writers, crew, associates, and even celebrity guests of Chelsea Lately are presented as an extended, dysfunctional 'family': pranking each other in childish ways; failed attempts to lie their way into gaining the favor of higher-status celebrities; bickering and arguing over mostly petty matters; and, constantly competing for show air time—and Chelsea's favor, while producing a nightly talk show.

Guest stars for After Lately include: Reese Witherspoon, Jennifer Aniston, Justin Bieber, Jane Fonda, Dave Grohl, James Van Der Beek, Jay Leno, Ross Mathews, Jenny McCarthy, Sharon Osbourne, Giuliana Rancic, Tori Spelling, Antonio Sabàto Jr., Loni Love, Natasha Leggero, Gary Valentine, Drew Pinsky, Geri Jewell, Vicki Gunvalson, Kate Beckinsale, Charlize Theron, Kathie Lee Gifford, Monica Potter, Kevin Nealon, Melissa Etheridge, Giancarlo Stanton, Kim Kardashian, Khloe Kardashian, Kourtney Kardashian, Kris Jenner.