The main event was for the TNA World Heavyweight Championship with Samoa Joe as Special Outside Enforcer between then-champion Kurt Angle and the challenger Christian Cage.

The next installment in the Against All Odds chronology was announced in late-November 2007 to take place on February 10, 2008, at the BI-LO Center in Greenville, South Carolina.

[2] In January 2008, In Demand listed a preview regarding Against All Odds, which advertised the event would hold the second-ever Barbed Wire Massacre.

[3] The South Carolina Athletic Commission originally gave TNA permission to hold Barbed Wire Massacre, however they receded their blessing prior to the event.

[7] The main event at Against All Odds was for the TNA World Heavyweight Championship with Samoa Joe as Special Outside Enforcer between then-champion Kurt Angle and the challenger Christian Cage.

[10] On the January 24, 2008 episode of Impact!, Cornette announced that Joe would be the Special Outside Enforcer at Against All Odds due him being controversially disqualified during the match.

Heading up to the match, Tomko explained he was not on either's side, despite being one-half of the TNA World Tag Team Champions with Styles.

when Team 3D attacked The Motor City Machine Guns (Alex Shelley and Chris Sabin; MCMG) and proclaimed they were going to eliminate the X Division.

[9] On the January 17, 2008 episode of Impact!, Lethal and MCMG accepted the agreement but only after including that Team 3D would have to weigh less than 275 pounds in order to compete in their matches in TNA.

[20] After the encounter, Roode accidentally punched Sharmell in the face, resulting in a storyline fractured jaw which sidelined her from appearing for the promotion and upsetting her real-life husband Booker T.[8] Following the event, Roode fired Brooks and higher her replacement Payton Banks on the January 10 episode of Impact!, setting up a match between the two at Against All Odds.

Two matches taking place at Against All Odds revolved around the Feast or Fired cases won at Turning Point by B.G.

[12] On the February 7, 2008 episode of Impact!, Cornette announced that Steiner and Williams would face at Against All Odds in which the winner would gain both cases.

Andrew Thomas, Earl Hebner, Rudy Charles, and Mark "Slick" Johnson participated as referees for the encounters.

[26] Eric Young defended the TNA World Beer Drinking Championship against James Storm, who was accompanied by Jackie Moore, in the fourth encounter.

The second involved Moore distracting the referee, at which time Rhino made his return from an injury and entered the ring to perform his signature Gore maneuver on Storm, giving Young the victory at seven minutes and forty-nine seconds to retain the TNA World Beer Drinking Championship.

[23] The TNA Women's Knockout Championship was defended by Awesome Kong, who was accompanied by Raisha Saeed, against ODB in a match lasting six minutes and fifty-four seconds.

During the match, Kong was positioned on the top of a padded turnbuckle which allowed ODB to lift her off and perform a powerbomb gaining a near-fall.

Afterwards, Saeed stood on the ring apron to distract ODB, allowing Kong to perform her signature Awesome Bomb maneuver and gain the pinfall to retain the TNA Women's Knockout Championship.

[24] The second-ever Barbed Wire Massacre was the sixth match on the card between Abyss and Judas Mesias, who was accompanied by Father James Mitchell.

Zone in Orlando, Florida, because the city of Greenville, SC refused to allow a match that violent to take place live.

Abyss won the contest after using the Black Hole Slam to drop Mesias onto a barbed-wire wrapped board.

[25] The next match pitted Booker T against Robert Roode, who was accompanied by Payton Banks, in a bout lasting nine minutes and seventeen seconds.

Afterwards, Roode began walking to the backstage area as Booker T followed continuing the fight as the referee counted out both men, ending the contest in a draw.

During the final minutes, both Sabin and Shelley were scripted to appear unconscious at ringside, which caused Lethal to have to fight off Devine and Team 3D alone.

Lethal then stood on the top of a padded turnbuckle and jumped off to perform an elbow drop on Devine through the table to win the match.

[28] Compared to rival World Wrestling Entertainment's No Way Out PPV event held on February 17, 2008, Against All Odds was rated higher as No Way Out was given a six out of ten by Dave Hillhouse.

The lowest rating of Sokol's review was given to the TNA World Tag Team Championship match with a four out of ten.

Keller felt the Barbed Wire Massacre "largely delivered" on what people "expected based on the build up.

[33] On the February 28, 2008, episode of Impact!, Storm defeated Young to win the TNA World Beer Drinking Championship in a Ladder match.

[28] After winning the TNA X Division Championship at Against All Odds, Jay Lethal went on to defend the title against Petey Williams at Destination X.