Agave weberi is a relatively short suckering species, the leafy trunks rarely more than 1 m (3 ft) tall.

Agave weberi was first described in 1901 in a publication authored by Jules Poisson, who attributed the name to Jean Francois Cels.

[9] A. weberi may be a cultivar derived from the wild species A. vivipara,[2] although an origin from A. sisalana or A. kewensis has also been suggested.

[9] It is believed to have originated in northeastern Mexico (San Luis Potosí, Tamaulipas), and is now naturalized in Texas and Florida in the United States and in the Northern Provinces in South Africa.

[5] Based on the belief that populations in Florida were a separate species, they were the subject of conservation concerns.