The species produces yellow blooms throughout late summer and early autumn, with some flowers becoming 2–3 inches (51–76 mm) wide.

[citation needed] Agave kewensis is endemic to Chiapas and Oaxaca, Mexico, where it thrives in arid montane zones.

The species is seen growing near abundant moss cover, which has water droplet buildup when its rains, but also keeps the plant somewhat cool during hot seasons.

[citation needed][2] Agave kewensis is commonly used as an ornamental plant for gardens, private collections, and botanical parks, but is being overcollected from its natural habitat in the wild, hence creating a population decline.

Other uses may include: brush for fires, medicinal purposes, and used for local cuisine (although the species petals and other plant matter can be toxic in great amounts).