Agonopterix flavicomella is a moth of the family Depressariidae.

It is found in North America, where it has been recorded from Alabama, Georgia, Illinois, Indiana, Kentucky, Maine, Michigan, Minnesota, North Carolina, Ohio, Tennessee, Virginia and West Virginia.

Adults are on wing from April to August and in October.

The larvae feed on Heracleum lanatum and Taenidia integerrima.

This article on a moth of genus Agonopterix is a stub.