His starring debut was in 1956 in the film "Bataclán mexicano'' alongside former Miss Universe Christiane Martel.

In 1958, he worked in the movie "Los Desarraigados", a film based on the play of the same name by author José Humberto Robles.

On the night of 29 May 1960, de Anda accompanied his girlfriend Ana Bertha Lepe to the cabaret "La Fuente'' located in Insurgentes Sur, where the actress was presenting her show.

Le[e went to her dressing room and de Anda to a table where Guillermo Lepe, his girlfriend's father, was already seated.

After Agustín's murder, Ana Bertha Lepe's career was severely affected; as she suffered a boycott led by her late boyfriend's father Raúl de Anda, which was joined by all the film producers, and she was no longer given work.