Laura Michelle Hollins[2] was born in Littleborough, Greater Manchester[3] to Roman Catholic parents who divorced and spent her early childhood in Failsworth.

[10][11] Deyn's working life started at a fish and chip shop in Stubbins, Rossendale, where she was a part-time server at the age of 13.

[15] Deyn's biography claims that she was "spotted" while shopping with fashion designer Henry Holland in Kentish Town, London.

[citation needed] In May 2007, she was featured on the cover of American Vogue, alongside Doutzen Kroes, Caroline Trentini, Raquel Zimmermann, Sasha Pivovarova, Jessica Stam, Coco Rocha, Hilary Rhoda, Chanel Iman and Lily Donaldson as "The World's Next Top Models.

[18] She has walked the runways for Chanel, Dolce & Gabbana, Burberry, Hermés, Dior, Lanvin, DKNY, Karl Lagerfeld, Moschino, Versace, Michael Kors, Zac Posen, Celine, Roberto Cavalli, Bottega Veneta, Proenza Schouler, Tommy Hilfiger, Stella McCartney, Viktor & Rolf, Max Mara, Oscar De La Renta, Ralph Lauren, Giles Deacon, Alexander Wang, Jean Paul Gaultier, Alberta Ferretti, Carolina Herrera, and Yves Saint Laurent.

[19] In June 2009, the Daily Mirror reported that Deyn had quit modeling to spend more time with her then boyfriend, singer-songwriter Miles Kane.

[32] In 2012, Deyn starred opposite Richard Coyle in Pusher, an English language remake of Nicolas Winding Refn's Danish film of the same name, where she played Flo, a strong-minded stripper.

[33] On 28 February 2012, Deyn played her first role on the West End stage, as Paula in François Archambault's comedy, The Leisure Society.

[35] In 2013, Deyn played the lead role in Electricity, a film adaptation of the novel by Ray Robinson, about the journey of a young woman with epilepsy.

[38] In 2017, Deyn began filming Hard Sun, a pre-apocalyptic [clarification needed] crime drama for the BBC at Hanstead Park in Bricket Wood, Hertfordshire.

[39] In 2018, Deyn appeared in the Netflix original movie The Titan as Dr. Freya and starred in Alex Ross Perry's Her Smell as Marielle Hell, bassist for the fictional band Something She.

[40][41][42] In 2010, Deyn collaborated with her younger sister Emily to create a line of T-shirts and tank tops for high street chain Uniqlo.

[47] In the 2000s, she dated musicians Josh Hubbard of The Paddingtons, Albert Hammond Jr. of the Strokes, Alex Greenwald of Phantom Planet, and Miles Kane of the Last Shadow Puppets.