The Air Force Safety Center is composed of the Deputy Chief of Safety/Executive Director and ten divisions at its Kirtland AFB location.

It oversees the aviation mishap investigative process, the collection and accuracy of flight safety data and the disposition of risk-mitigating actions.

The division is responsible for the development and content of formal occupational safety-related training courses for supervisors and safety professionals.

The Space Safety Division mission is to preserve combat space-power by anticipating, reducing, and preventing mishaps.

The division leadership chairs several multi-agency boards performing safety oversight for all nuclear, conventional and DE (laser and radio-frequency) weapons.

The division includes experts from aircraft operations, medicine, physiology, psychology and occupational safety, all focused on the human element in mishap prevention.

It is responsible for the quality control of Human Factors Analysis and Classification System (HFACS) coding in all Class A mishaps.

The Division analyzes data sources to identify human factor hazards and provides research-based policy recommendations on mitigation strategies.

The education and training encompasses all safety disciplines: aviation, occupational, weapons, space and missiles; ensuring mission-ready capabilities are preserved for the U.S. Air Force, and is delivered to approximately 2,400 students through nine professional courses in 60 sessions, ranging from three days to seven weeks.

The Office of the Staff Judge Advocate provides legal advice and general counsel on all aspects of Air Force mishap prevention programs and safety investigations.

The Public Affairs Division supports the Chief of Safety's communication program by providing service members and the general public timely and accurate information to raise awareness and improve understanding of the Air Force Safety Center mission and its role in mishap prevention, and to promote mishap prevention Air Force-wide.

The division manages the center's public website and social media programs; generates news releases, photos and video products for Air Force-wide distribution; and engages with the news media to ensure the accurate reporting of safety programs and mishap prevention efforts.

On Dec. 31, 1971, the Air Force Inspection and Safety Center was activated, replacing the 1002nd Inspector General Group.