[5] In addition to changes in the materials that dope is applied to, the methods of application have also been refined to reduce shrinking, improve adherence and increase lifespan.

The medical profession across several nations became aware of this threat just prior to the First World War, and promoted the need for adequate workplace ventilation as a mitigating measure in factories where doping was performed.

[12] Due to more powerful engines and advanced aerodynamic techniques, aluminium (and subsequently composites) supplanted fabric as the primary material used in the aviation industry by the latter half of the 20th century.

Examples of common mistakes include mixing dope with other chemicals, using it on the wrong fabrics, or applying it to contaminated or improperly prepared surfaces.

[14] Among the hypotheses for the 1937 Hindenburg airship disaster, the Incendiary Paint Theory, presented by Addison Bain,[15] is that a spark between inadequately grounded fabric cover segments of the Hindenburg started the fire, and that the spark had ignited the "highly flammable" outer skin doped with iron oxide and aluminum-impregnated cellulose acetate butyrate, which remain potentially reactive even after fully setting.

The US National Transportation Safety Board investigation determined that the layers and types of doping that had been used on the aircraft did not have "the best adhesive qualities" and referred to "the Poly-Fiber Covering and Painting Manual" for proper processes to use.