After studying the Quran at Al-Kutab in Saudi Arabia,[4] Al-Mana traveled to Egypt, where she finished school.
Her dissertation title was Economic Development and its Impact on the Status of Women in Saudi Arabia.
Prior to the demonstration, the women had sent a petition to then-Prince Salman bin Abdulaziz, the governor of Riyadh at the time, requesting that he and King Fahad move to lift the ban.
[citation needed] In 2011, al-Mana held workshops on the male guardianship system in the cities of Riyadh, Jeddah and Khobar[5] as part of the anti male-guardianship campaign.
The program "will provide scholarships for Saudi women to study global health at the UO, fund seed grants for faculty research, help implement an annual series of speakers and workshops, and support internships for UO students in the Saudi kingdom — the UO’s first fully funded international internships in global health.
[14] In May 2018 she was reported arrested, together with other female Saudi activists, Loujain al-Hathloul, Iman al-Nafjan, Aziza al-Yousef and Madeha al-Ajroush, and two male women's-rights activists,[15][16] though Aisha Al-Mana and Madeha al-Ajroush were released after a few days.