[7][8] Derbez began her career as a model at age 15.

[6] She studied visual arts at the School of Visual Arts and acting at the Actors Studio, both in New York City.

[10] Her paternal grandmother is the actress Silvia Derbez.

[11] Derbez started dating Mauricio Ochmann after filming A La Mala in 2014;[12] the couple married in 2016.

[13] On 27 February 2018 she gave birth to their daughter, named Kailani Ochmann.