[5] In August 2012, Missick announced that she would be seeking the PNP's nomination to stand in Leeward District 5, Providenciales for the 2012 general election.

[1] Due to provisions in the new 2011 Constitution of the Turks and Caicos Islands, this required her to renounce any foreign allegiance she held by virtue of her act.

Missick, though the only U.S.-born candidate, was far from the only one to had to take quick action to renounce foreign citizenship; Bahamas-born People's Democratic Movement deputy leader Sharlene Cartwright-Robinson and several other members of her party were also affected, and the newly formed People's Progressive Party stood in danger of having all of its candidates disqualified.

[7] She emerged victorious in the election, and the week afterward was named as Deputy Premier and Minister of Education, Youth, Sports and Culture.

She was appointed by Premier Charles Misick to serve as the Leader of Government Business and Minister of Infrastructure, Housing Planning and Development on 22 January 2021.