[1][2] In the 1990s, Pacino starred in numerous films, including Frankie and Johnny with Michelle Pfeiffer (1991), Glengarry Glen Ross (1992; as Richard Roma), Scent of a Woman with Chris O'Donnell (1992), Carlito's Way with Sean Penn (1993), Heat with Robert De Niro (1995), Donnie Brasco with Johnny Depp (1997), The Devil's Advocate with Keanu Reeves (1997), and Any Given Sunday with Cameron Diaz (1999).
The following year, he appeared in the action thriller film Righteous Kill, again with De Niro.
In 2019, he had a minor role in Quentin Tarantino's comedy drama film Once Upon a Time in Hollywood, and he portrayed Jimmy Hoffa in The Irishman, the fourth film on which he and De Niro worked together.
Pacino's television work includes the 2003 HBO miniseries Angels in America, in which he played American lawyer and prosecutor Roy Cohn, and the 2010 made-for-television biopic You Don't Know Jack, in which he played American pathologist and euthanasia proponent Dr. Jack Kevorkian.
He also co-starred in the conspiracy drama streaming television series Hunters (2020–2023).