His honorary awards include the Honorary Golden Lion at Venice Film Festival in 1994, the Golden Globe Cecil B. DeMille Award in 2001, the National Medal of Arts in 2011, and the Kennedy Center Honors in 2016.

Pacino won the Academy Award for Best Actor for his portrayal of a blind retired Lieutenant Colonel in the drama Scent of a Woman (1992).

On television, Pacino won the Primetime Emmy Award for Outstanding Lead Actor in a Miniseries or a Movie, the Golden Globe Award for Best Actor – Miniseries or Television Film, and the Screen Actors Guild Award for Outstanding Actor in a Miniseries or Television Movie for his portrayals of Roy Cohn in the HBO miniseries Angels in America (2003) and the Jack Kevorkian the HBO biopic You Don't Know Jack (2010).

He was Emmy-nominated for his performance as the title role in the HBO film Phil Spector (2013).

He received a nomination for the Golden Globe Award for Best Actor – Television Series Drama for his dual role as a Nazi evading arrest in the Amazon Prime Video conspiracy drama Hunters (2020–2023).