State Route 207 (SR 207) is a 13.959-mile-long (22.465 km) route that serves as a connection between U.S. Route 72 (US 72) in Rogersville in Lauderdale County and the Tennessee state line.

The southern terminus of SR 207 is located at its intersection with US 72 opposite CR 91 in southern Rogersville.

[2] From this point, the route travels in a northerly direction towards Anderson.

From Anderson, the route turns to the northeast before resuming a more northerly track after its junction with SR 99 as it enters Tennessee.

[3] The entire route is in Lauderdale County.