[3] He has written 11 books—his latest, a cultural memoir Laugh Lines: My Life Helping Funny People Be Funnier was published by Abrams Books in 2020.

[2] During his five years at Saturday Night Live (1975–1980), Zweibel wrote many iconic sketches, including the Samurai for John Belushi, and created the characters of Roseanne Roseannadanna and Emily Litella, both portrayed by Gilda Radner.

On Broadway, he co-wrote Fame Becomes Me with Martin Short, and collaborated with Billy Crystal on the Tony Award-winning production of 700 Sundays.

Taking to the stage himself, Zweibel is an ensemble performer in Celebrity Autobiography at New York's Triad Theater— and is a sought after keynote speaker.

He co-wrote and co-produced Here Today (2021) with Billy Crystal (who also directed and starred alongside Tiffany Haddish), and was the co-writer for Dragnet (1987 film), The Story of Us (1999) and North (1994).

by the State University of New York, and in 2010, he was given the Ian McLellan Hunter Lifetime Achievement Award by the Writers Guild of America, East.