[1] On January 14, 2015, Man Seeking Woman, a television comedy series created by Rich (and based on his short story collection The Last Girlfriend on Earth), premiered on the cable channel FXX.

[7] Rich has had pieces published in McSweeney's, The Believer,[8] GQ,[9] The Observer magazine,[10] Mad magazine,[11] Vanity Fair,[12] UK Glamour, Italian GQ, Italian Granta,[13] NPR.com,[14] NPR's "Selected Shorts,"[15] and The Barcelona Review,[16] among other publications.

His writing has also been selected for numerous anthologies including The Best of McSweeney's,[17] and I Found This Funny, edited by Judd Apatow.

[18] In 2013, Sony Pictures acquired the film rights to Rich's four-part novella Sell Out, which was originally published by The New Yorker that same year.

[20] Rich is slated to write the script based on the illustrated book Unicorn Executions, to be produced by Universal Studios.

Reception was favorable, with The Washington Post praising the book as "hilarious," declaring, "it just might be the best one-night stand you'll ever have.

"[23] The Last Girlfriend on Earth was given a pilot order by FX within a week of its publishing as Man Seeking Woman.

[24] The show was officially ordered by FXX with the leading cast of Jay Baruchel, Eric Andre, Britt Lower and Maya Erskine, with Rich as show-runner and executive producer, making him one of the youngest creators in TV history.

[33] In 2012, Rich published his second novel, What in God's Name, which The New York Times Book Review compared to Douglas Adams's The Hitchhiker's Guide to the Galaxy.

Scheduled for a 10-week run at the Hudson Theatre, the production features a rotating cast of four performers at a time, which initially included John Mulaney, Fred Armisen, Renée Elise Goldsberry and Richard Kind for the first five weeks of performances,[35] and Lin-Manuel Miranda, Chloe Fineman, Andrew Rannells, Aidy Bryant, Sam Richardson and others in subsequent weeks.

[36] Simon Rich has called Woody Allen his hero, specifically citing his short-story collections as major influences.