While working at a call center, she found a job listing for a volunteer games journalist position that inspired a career in journalism.

[4] Later that year, she was involved in a staff walkout until the company issued a statement addressing sexual harassment allegations made by former editor Kallie Plagge.

[21][22] In December 2024, Pearce revealed that she was leaving Santa Monica Studio, citing her desire for the flexibility to visit her family in Australia more often as the key factor in her decision.

[23] Pearce is the host of the Play, Watch, Listen podcast, along with Troy Baker, Mike Bithell, and Austin Wintory.

[25] She was a founding host of the Kinda Funny Xcast, but left the show several months after its premiere due to scheduling conflicts with her new job at Santa Monica Studio.

[28] Pearce was briefly banned from Twitch following a DMCA takedown notice sent by Nintendo after she live-streamed herself reacting to already-published preview footage of its game, The Legend of Zelda: Tears of the Kingdom, five days before its release.

[29] Pearce appears as Halley in the 2024 film V/H/S/Beyond, in the final segment "Stowaway", directed by Kate Siegel and written by Mike Flanagan.

[35][36] She co-hosted the inaugural Video Game Accessibility Awards with AbleGamers's chief operating officer Steven Spohn in November 2020,[37][32] and returned to present the second event in March 2022.

[5][39][40] In 2019, she was subject to harassment after the Entertainment Software Association, the organiser of the E3 gaming expo, leaked the personal information of E3 2019 media attendees to the public.