[2] New taxes levied in the early months of 1910 led to Isa Boletini's activity to convince Albanian leaders who had already been involved in a 1909 uprising to try another revolt against the Ottoman Empire.

After two weeks of fierce fighting the Albanian forces withdrew to the Drenica region, whereas the Ottoman army took possession of the cities of Prizren and Yakova (now Gjakova).

During the first months of 1910, Isa Boletini tried to coordinate forces for a new insurrection by visiting the Albanian clans, which had taken refuge in Montenegro after the failure of a previous minor uprising in 1909.

Albanian leaders held two other meetings in Peja and Ferizaj, where they took the oath of besa to be united against the new Ottoman government policy of centralization.

The Ottoman government declared martial law and sent a military expedition of 16,000 men led by Shefqet Turgut Pasha who went to Skopje in April 1910.

By government orders[4][8] part of the force proceeded in the direction of Scutari (now Shkodër), while another column marched toward the Debre region (now known as Dibër in Albania, and Debar in the Republic of North Macedonia).

The first column marching to Scutari managed to capture the Morinë pass, after fighting with the Albanian forces of Gash, Krasniq and Bytyç areas, led by Zeqir Halili, Abdulla Hoxha, and Shaban Binaku.

[9] The Ottoman army, made up of irregular Kurds, flogged the leaders in public, burnt villages, and drove some 150,000 from their homes, two thirds being Serbs.

[15][16] The Albanian revolts of 1910 and 1912 were a turning point that impacted the Young Turk government which increasingly moved from a policy direction of pan-Ottomanism and Islam toward a singular national Turkish outlook.