Born in Falmouth, Trelawny Parish, Jamaica, Huie moved to Kingston when he was 16 years old;[1] in the 1930s he became part of the "Institute Group" at the Institute of Jamaica, where he received his first formal training with Armenian artist Koren der Harootian.
[2][3] In the early 1940s he worked as an assistant to Edna Manley while she taught at Kingston's Junior Centre.
[2][8] Some of his pieces expressed sociopolitical and nationalist themes, and many of his early paintings related in some way to manual labor.
[9] His painting Miss Mahoghany caused controversy twice in his lifetime, first when it was unveiled in 1960 and again in 2000 when it was featured in Air Jamaica's Skywritings magazine which resulted in its removal.
Huie received the Jamaican Government Award for the Best Painting in the annual National Exhibition in 1962.