He then joined the faculty of the Worcester Polytechnic Institute, becoming a full professor and rising to department head in 1989.

[1] Sacco served as the Dean of the Edward E. Whitacre Jr. College of Engineering at Texas Tech University, from January 1, 2011, to August 16, 2022.

Sacco flew as a payload specialist on STS-73, which launched on October 20, 1995, and landed at the Kennedy Space Center on November 5, 1995.

[1] Sacco was originally chosen as the payload specialist for the ill-fated STS-107 mission, which ended in the Space Shuttle Columbia disaster.

He trained with the other six astronauts for two months until NASA and the U.S. government decided to replace him with Israeli payload specialist Ilan Ramon.