[1] Puello faced Abrahan Peralta for the vacant WBA Fedelatin and WBC Latino super-lightweight titles on 24 February 2017.
After beating Patrick López by a seventh-round technical knockout on 24 June 2017,[3] Puello was booked to make his first WBA Fedelatin and Latino title defenses against Ricardo Gutierrez on 18 November 2017.
The bout was scheduled as the main event of a card which took place at the Coliseo Carlos 'Teo' Cruz in Santo Domingo, Dominican Republic on 27 July 2019.
[9] Puello made his first WBA interim title defense against Cristian Rafael Coria on 17 December 2020, following a seventeen-month absence from the sport.
The fight was booked as the co-headliner to the WBA interim minimumweight title bout between Erick Rosa and Ricardo Astuvilca.
[17] On 9 March 2022 the undisputed light welterweight champion Josh Taylor was ordered by the WBA to make a mandatory title defense against Puello.
[29] Puello was scheduled to face Gary Antuanne Russell for the interim WBC super lightweight title at MGM Grand Garden Arena in Las Vegas on 15 June 2024.
[32][33] Puello is scheduled to make the first defense of his WBC super lightweight title against Sandor Martin at Barclays Center in Brooklyn, NY on March 1, 2025.