Emerging evidence suggests that "even drinking within the recommended limits may increase the overall risk of death from various causes, such as from several types of cancer".
[36] One systematic analysis found that "The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks per week".
[38] Excessive drinking during pregnancy, especially in the first eight to twelve weeks, is associated with fetal alcohol spectrum disorders such as abnormal appearance and behavioral problems.
Even one or two drinks, including beer, may reduce milk intake by 20 to 23%, leading to increased agitation and poor sleep patterns.
The recommended limits for daily or weekly consumption provided in the various countries' guidelines generally apply to the average healthy adult.
[60][61][62] Moreover, studies suggest even moderate alcohol consumption may significantly impair – neurobiologically beneficial and -demanding – exercise (possibly including the recovery and adaptation).
[71] Polymeal and most versions of the Mediterranean diet recommend a moderate amount of red wine, such as 150 mL (about one glass) every day, in combination with other several food items.
[72][73][74][75] The United Kingdom's National Health Service also recommends a Mediterranean diet to reduce cardiovascular disease risk.
[76][77] The WHO has stated that there is currently no conclusive evidence that the potential benefits of moderate alcohol consumption for cardiovascular disease and type 2 diabetes outweigh the increased cancer risk associated with these drinking levels for individual consumers.