[1] Caraballo was a staff attorney at the LGBTQ Law Project at the New York Legal Assistance Group, representing LGBT individuals seeking asylum and other immigrants.

[1] The New York Times described Caraballo as an expert on transgender issues;[2] she has spent years monitoring anti-LGBT rhetoric online.

[13] Caraballo has been outspoken about what she sees as anti-LGBT legislation and policies; rhetoric from prominent individuals; and inadequate social media moderation surrounding the topic.

[8][16] Later that year, Caraballo was critical of Elon Musk's actions after acquiring Twitter, including his decision to reinstate accounts that had been suspended for threats, harassment, or misinformation.

[17] In a tweet published on December 29, 2022, Caraballo suggested that the arrest of American-British social media personality Andrew Tate in Romania on human trafficking charges was facilitated by a video he posted online revealing his location by showing the name of a Romanian pizzeria.

[18][21] The day before the publication of the UK National Health Service's Cass Review on gender services for children and young people in April 2024, Caraballo tweeted that the report was holding transgender health care to an "impossible standard" and had "disregarded nearly all studies" since double-blind controlled studies could not be used to evaluate the effects of transgender hormone therapy.